Technology

Ⅲ.

Switching PCR

Liquid Biopsy · Somatic Mutation​

Principle : Switching™

    HB Switching PCR technology is an Ultra-High Sensitive PCR platform with a Limit of Detection of 10⁰ (1 to 9) copies per reaction. A limitation of conventional PCR or Real-Time PCR is low sensitivity that may lead to false positive results.

This is addressed by providing an alternative PCR technique with significantly higher accuracy.

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Conventional Liquid Biopsy for

Nucleic Acid Analysis

Low concentrations of target genetic materials in body fluids such as blood and urine.

Requires diagnostic tools with high sensitivity, such as Nested PCR, to detect extremely low concentrations.

False negative results are possible.

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Switching PCR

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Limit of Detection of 10⁰ copies/rxn

High Sensitivity

Liquid Biopsy

Early detection of cancer and other diseases.

Minimally-invasive and quicker analysis

Benefits

Target genetic materials exist at low concentrations in body fluids such as blood, urine.

Diagnostic tools with high sensitivity, such as Nested PCR, are required to detect extremely low concentrations.

False negative results are possible.​

Reduce false positives by detecting extremely low concentrations of genetic material with high sensitivity.

Accurate diagnosis with reduced run time and low risk of cross-contamination compared to Nested PCR.

Compatible with conventional PCR and Real-Time PCR

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