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Switching™ PCR Technology

Ultra-High Sensitive PCR Technology

Principle

    HB Switching™ PCR Technology is an Ultra-High Sensitive PCR platform with a Limit of Detection of <10¹ copies per reaction. A limitation of conventional PCR or Real-Time PCR is low sensitivity that may lead to false positive results.

This is addressed by providing an alternative PCR technique with significantly higher accuracy.

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Conventional Liquid Biopsy

for Nucleic Acid Analysis

Low concentrations of target genetic materials in body fluids such as blood and urine.

Requires diagnostic tools with high sensitivity, such as Nested PCR, to detect extremely low concentrations.

False negative results are possible.

Advantages of switching™ PCR

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Switching™ PCR

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Limit of Detection of <10¹ copies/rxn

High Sensitivity

Liquid Biopsy

Early detection of cancer and other diseases.

Minimally-invasive and quicker analysis

Benefits

Low concentrations of target genetic materials in body fluids such as blood and urine.

Requires diagnostic tools with high sensitivity, such as Nested PCR, to detect extremely low concentrations.

False negative results are possible.

Reduce false positives by detecting extremely low concentrations of genetic material with high sensitivity.

Accurate diagnosis with reduced run time and low risk of cross-contamination compared to Nested PCR.

Compatible with conventional PCR and Real-Time PCR

Related Products

HB SwitchPlex™ kit detects low concentrations (L.O.D. <10⁰ copy/rxn) of target genes with high reproducibility and accuracy making it highly competitive from a technical perspective.

HB SwitchPlex™ T790M Kit is used to prescribe the secondary targeted anticancer drug called Osimertinib to patients with positive results with EGFR T790M mutation.
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HBSwitchPlex™ Respiratory Virus Duplex Kits consist of 4 products derived from HB SBDE™ Switching PCR technology, an Ultra-High Sensitive PCR platform to diagnose 7 respiratory viruses. Each kit has a high sensitivity with a limit of detection of 10⁰ copies and detects.