Technology
Switching™ PCR Technology
Ultra-High Sensitive PCR Technology
Principle
HB Switching™ PCR Technology is an Ultra-High Sensitive PCR platform with a Limit of Detection of <10¹ copies per reaction. A limitation of conventional PCR or Real-Time PCR is low sensitivity that may lead to false positive results.
This is addressed by providing an alternative PCR technique with significantly higher accuracy.
Conventional Liquid Biopsy
for Nucleic Acid Analysis
Ⅰ
Low concentrations of target genetic materials in body fluids such as blood and urine.
Ⅱ
Requires diagnostic tools with high sensitivity, such as Nested PCR, to detect extremely low concentrations.
Ⅲ
False negative results are possible.
Advantages of switching™ PCR
Switching™ PCR
Limit of Detection of <10¹ copies/rxn
High Sensitivity
Liquid Biopsy
Early detection of cancer and other diseases.
Minimally-invasive and quicker analysis
Ⅰ
Low concentrations of target genetic materials in body fluids such as blood and urine.
Ⅱ
Requires diagnostic tools with high sensitivity, such as Nested PCR, to detect extremely low concentrations.
Ⅲ
False negative results are possible.
Ⅰ
Reduce false positives by detecting extremely low concentrations of genetic material with high sensitivity.
Ⅱ
Accurate diagnosis with reduced run time and low risk of cross-contamination compared to Nested PCR.
Ⅲ
Compatible with conventional PCR and Real-Time PCR
Related Products
HB SwitchPlex™ kit detects low concentrations (L.O.D. <10⁰ copy/rxn) of target genes with high reproducibility and accuracy making it highly competitive from a technical perspective.