Technology
SBDE™ PCR Technology
SBDE™ (Specific Bi-Directional Extension) is a One-Step Multiplexing PCR technology with high sensitivity and specificity. It has the capability to differentiate between homozygosity and heterozygosity in Single Nucleotide Polymorphisms (SNPs) in addition to detecting Short Tandem Repeats (STR).
Conventional PCR techniques require multiple parallel reactions or sequencing of the PCR product to differentiate between homozygote and heterozygote genotypes accurately.
HB SBDE™ is a highly accurate, One-step Multiplexing PCR technique that inserts arbitrary sequences to identify homozygote and heterozygote genotypes via gel electrophoresis or dual-labelled probe.
Related Products
SBDE-Plex™
Companion Dx Kit
HB SBDE-Plex™ products are companion diagnostic tests that use SBDE™ technology, compatible with both conventional and Real-Time PCR in precision medicine. It determines the optimal therapeutic drug for a patient, based on their genotype to reduce risk for adverse side effects or mortality.