Products
miRDx™
BKV KitBKV Diagnostics Using miRNA Biomarkers
Intro
Infection in Childhood
The BK virus is a type of polyomavirus that most people first become infected with during childhood. The initial infection is usually asymptomatic, and the virus can remain dormant in the cells of the kidneys or urinary tract for life. For individuals with a healthy immune system, the BK virus acquired in childhood typically does not cause any problems.
After Kidney Transplantation
The global incidence of kidney failure and transplants is rising. Kidney transplant patients receive immunosuppressive drugs to prevent organ rejection, which can lead to BKV nephropathy caused by the proliferation of the BK virus. However, in immunocompromised or immunosuppressed patients, the virus can reactivate due to weakened immunity.
BKV Diagnostics Using miRNA Biomarkers
Liquid Biopsy
Advantage of miRNA Biomarker
Non-invasive
Quick, Easy, Repetitive
Convenient
Disease Monitoring
Enabling
Early Diagnosis
Sample Stability
Advantage of miRNA Biomarker
HB miRDx™
BKV Kit
High Performance
Early Detection
BK viral DNA detection is usually time consuming, and although various techniques are developed to reduce the reaction time, Real time PCR and quantitative validation still require some time. Whereas, detecting BK virus using miRNA has high accuracy and sensitivity which allows to detect BK virus 1.5 to 2 month earlier than the viral DNA detection technology.
※ Clinical Effectiveness (Confirmation) Evaluation Final Report - Kyung Hee University Hospital at Gangdong
