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miRDx™

BKV Kit

BKV Diagnostics Using miRNA Biomarkers

Intro

Infection in Childhood

The BK virus is a type of polyomavirus that most people first become infected with during childhood. The initial infection is usually asymptomatic, and the virus can remain dormant in the cells of the kidneys or urinary tract for life. For individuals with a healthy immune system, the BK virus acquired in childhood typically does not cause any problems.

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After Kidney Transplantation

The global incidence of kidney failure and transplants is rising. Kidney transplant patients receive immunosuppressive drugs to prevent organ rejection, which can lead to BKV nephropathy caused by the proliferation of the BK virus. However, in immunocompromised or immunosuppressed patients, the virus can reactivate due to weakened immunity.

BKV Diagnostics Using miRNA Biomarkers

Liquid Biopsy

Advantage of miRNA Biomarker

Non-invasive

Quick, Easy, Repetitive

Convenient
Disease Monitoring

Enabling
Early Diagnosis

Sample Stability

Advantage of miRNA Biomarker

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HB miRDx™

BKV Kit
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High Performance

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Early Detection

BK viral DNA detection is usually time consuming, and although various techniques are developed to reduce the reaction time, Real time PCR and quantitative validation still require some time. Whereas, detecting BK virus using miRNA has high accuracy and sensitivity which allows to detect BK virus 1.5 to 2 month earlier than the viral DNA detection technology.

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※ Clinical Effectiveness (Confirmation) Evaluation Final Report - Kyung Hee University Hospital at Gangdong

Related Technology

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miRDx™ Technology

HB miRDx™ is one of three miRNA detection technologies (RT-qPCR based) in the world. This technique possesses multiplexing capabilities and allows for accurate sequencing of PCR products, in addition to boasting high sensitivity and specificity.

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